Klonopin, a benzodiazepine, is available as scored tablets with a K-shaped perforation containing 0.5 mg of clonazepam and unscored tablets with a K-shaped.
Updated April 11, 2016.
Patients, their caregivers, and families should be informed that AEDs increase the risk of suicidal thoughts and behavior and should be advised of the need to be alert for the emergence or worsening of the signs and symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts, behavior, or thoughts about self-harm. Behaviors of concern should be reported immediay to healthcare providers.
An increased risk of congenital malformations associated with the use of benzodiazepine drugs has been suggested in several studies.
The relative risk for suicidal thoughts or behavior was higher in clinical trials for epilepsy than in clinical trials for psychiatric or other conditions, but the absolute risk differences were similar for the epilepsy and psychiatric indications.
Patients, their caregivers, and families should be counseled that AEDs, including Klonopin, may increase the risk of suicidal thoughts and behavior and should be advised of the need to be alert for the emergence or worsening of symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts, behavior, or thoughts about self-harm.
Medscape - Seizure, panic disorder-specific dosing for Klonopin (clonazepam), frequency-based adverse effects, comprehensive interactions, contraindications.
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Learn about indications, dosage and how it is supplied for the drug Klonopin (Clonazepam).
The effectiveness of Klonopin in long-term use, that is, for more than 9 weeks, has not been systematically studied in controlled clinical trials. The physician who elects to use Klonopin for extended periods should periodically reevaluate the long-term usefulness of the drug for the individual patient (see DOSAGE AND ADMINISTRATION ).
There is no body of evidence available to answer the question of how long the patient treated with clonazepam should remain on it.
Initial: Not to exceed 1.5mg/day divided into 3 doses. Titrate: May increase in increments of 0.5-1mg every 3 days until seizures are controlled or until side effects.
To reduce somnolence, may give 1 dose at hs. Tab, Disintegrating Peel back foil on blister; do not push tab through foil. Using dry hands, remove tab and place it in mouth.
Tab Swallow whole w/ water.
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History of sensitivity to benzodiazepines, significant liver disease, acute narrow angle glaucoma.
Assess for drug/benzodiazepine hypersensitivity, significant liver disease, acute narrow angle glaucoma, mental depression, history of drug or alcohol addiction, renal/hepatic impairment, chronic respiratory diseases, pregnancy/nursing status, and possible drug interactions.
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Benzodiazepine; has not been established.
Detailed dosage guidelines and administration information for Klonopin (clonazepam). Includes dose adjustments, warnings and precautions.
The tablets should be administered with water by swallowing the tablet whole. Clonazepam is available as a tablet.
Approval History Calendar Drug history at FDA.
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